
The Devor lab
research on neuropathic pain and pain-free surgery
Selected
Devor M, Rappaport I, Rappaport ZH. (2015)
Does the Golem feel pain? Moral instincts and ethical dilemmas concerning suffering and the brain. Pain Pract. 15:497-508. doi:10.1111/papr.12207
​
Vaso A, Adahan HM, Gjika A, Zahaj S, Zhurda T, Vyshka G, Devor M. (2014)
Peripheral nervous system origin of phantom limb pain. Pain 155:1384-91
​
Fried K, Sessle B, Devor M. (2011)
The paradox of pain from tooth pulp: low-threshold "algoneurons"? Pain 152:2685-89.
​
Nissenbaum J, Devor M, Seltzer Z, Gebauer M, Michaelis M, Tal M, Dorfman R, Abitbul-Yarkoni M, Lu Y, Elahipanah T, delCanho S, Minert A, Fried K, Persson A-K, Shpigler H, Shabo E, Yakir B, Pisanté A, Darvasi A. (2010)
Susceptibility to chronic pain following nerve injury is genetically affected by CACNG2. Genome Research, 20:1180-1190.
​
Devor M. (2009)
Ectopic discharge in Aβ afferents as a source of neuropathic pain. Experimental Brain Research 196:115-128.
​
Lu J, Sherman D, Devor M, Saper CB. (2006)
A putative flip-flop switch for control of REM sleep. Nature. 441: 589-594.
Niv D, Gofeld M, Devor M. (2003)
Causes of pain in degenerative bone and joint disease: a lesson from vertebroplasty. Pain 105:387-392.
Raber, P. and Devor, M. (2002)
Social variables affect pain phenotype in the neuroma model of neuropathic pain. Pain 97 139-150.
Devor, M. and Zalkind, V. (2001)
Reversible analgesia, atonia, and loss of consciousness on bilateral intracerebral microinjection of pentobarbital. Pain 94:101-112.
Devor, M. (1999)
Unexplained peculiarities of the dorsal root ganglion. Pain suppl.6: S27-S35.
Amir, R., Michaelis, M. and Devor, M. (1999)
Membrane potential oscillations in dorsal root ganglion neurons: role in normal electrogenesis and in neuropathic pain. Journal of Neuroscience 19: 8589-8596.
Mogil, J.S., Wilson, S.G., Bon, K., Lee, S.E., Chung, K., Raber, P., Pieper, J.O., Hain, H.S., Belknap, J.K., Hubert, L., Elmer, G.I., Chung, J.M. and Devor, M. (1999)
Heritability of nociception I: Responses of 11 inbred mouse strains on 12 measures of nociception. Pain 80: 67-82.
Amir, R. and Devor, M. (1996)
Chemically-mediated cross-excitation in rat dorsal root ganglia. Journal of Neuroscience 16: 4733-4741.
​
Rappaport, Z.H. and Devor, M. (1994)
Trigeminal neuralgia: the role of self-sustaining discharge in the trigeminal ganglion (TRG). Pain 56: 127-138.
​
Devor, M., Govrin-Lippmann, R. and Angelides, K. (1993)
Na+ channel immuno-localization in peripheral mammalian axons and changes following nerve injury and neuroma formation. Journal of Neuroscience 13: 1976-1992.
​
Devor, M. and Raber, P. (1990)
Heritability of symptoms in an animal model of neuropathic pain. Pain 42:51-67.
​
Devor, M., Govrin-Lippmann, R. and Raber, P. (1985)
Corticosteroids suppress ectopic neural discharge originating in experimental neuromas. Pain 22:127-137.
​
Wall, P.D. and Devor, M. (1983)
Sensory afferent impulses originate from dorsal root ganglia as well as from the periphery in normal and nerve injured rats. Pain 17: 321-339.
Devor, M, and Wall, P.D. (1983)
Reorganization of the spinal cord sensory map after peripheral nerve injury. Nature 276: 76-76.
Govrin-Lippmann, R. and Devor, M. (1978)
Ongoing activity in severed nerves: source and variation with time. Brain Research 159: 406-410
Devor, M. (1975)
Neuroplasticity in the sparing or deterioration of function after early olfactory tract lesions. Science 190: 998-1000.
Recent
Baron M, Vaso K, Ibraheem A, Minert A, Devor M. (2025)
Molecular and cellular targets of GABAergic anesthetics in the mesopontine tegmentum that enable pain-free surgery. Pain 166:1549-1564. doi: 10.1097/j.pain.0000000000003504.
Devor M. (2025)
Experiencing pain: perspectives of Patrick D. Wall-founding editor of the journal PAIN. Pain 166:11-19. doi: 10.1097/j.pain.0000000000003480.
Baron M, Devor M. (2024)
Neurosteroids foster sedation by engaging tonic GABAA-Rs within the mesopontine tegmental anesthesia area (MPTA). Neurosci Lett. ;843:138030. doi: 10.1016/j.neulet.2024.138030.
Devor M. (2024)
Pain in osteoarthritis: Driven by intrinsic rather than extrinsic joint afferents and why this should impact treatment. Interventional Pain Medicine 3: 1-7.
Baron M, Devor M. (2023)
From molecule to oblivion: dedicated brain circuitry underlies anesthetic loss of consciousness permitting pain-free surgery. Front. Mol. Neuroscience 16:1197304. doi: 10.3389/fnmol.2023.1197304.
Tal M, Minert A, Devor M. (2023)
Resurgent neuropathic discharge: an obstacle to the therapeutic use of neuroma resection? Pain 164:349-361. doi: 10.1097/j.pain.02704.
Baron M, Vaso K, Avigdor T, Charit Y, Minert A, Devor M.(2022)
Anesthetic loss of consciousness induced by chemogenetic excitation of mesopontine effector neurons. Exp Neurol. 357:114169. doi:10.1016/j.expneurol.2022. 114169.
Baron M, Minert A, Yatziv S and Devor M. (2022)
Nerves, Pain and Consciousness. Front. Young Minds. 10:744643. doi: 10.3389/frym.2022.744643
Baron M. Devor M. (2022)
Might pain be experienced in the brainstem rather than in the cerebral cortex? Behav.Brain Res 427:113861. doi: 10.1016/j.bbr.2022.113861.
Shai-Lee Yatziv S-l, Yudco O, Vaso K, Mizrahi A, Devor M. (2021)
Anesthesia in mice activates discrete populations of neurons throughout the brain. J. Neuroscience Research 99: 3284-3305, doi:10.1002/jnr.24950.
Yatziv S-l, Strumza N, Minert A, Baron M, Devor M. (2021)
A nodal point for brain‑state transitions: the mesopontine tegmental anesthesia area (MPTA) in mice. Experimental Brain Research 239:3255-3266 doi:org/10.1007/s00221-021-06204-7
Avigdor T, Minert A, Baron M., Devor, M. (2021)
Paradoxical anesthesia: Sleep-like EEG during anesthesia induced by mesopontine microinjection of GABAergic agents. Experimental Neurology 343:113760
Lellouche Y, Minert A, Schreiber C, Aroch I, Vaso K, Fishman Y, Devor M. (2020)
Individual mesopontine neurons implicated in anesthetic loss-of-consciousness employ separate ascending pathways to the cerebral cortex. Neuroscience 432:188-204.
Minert A, Baron M, Devor M. (2020)
Reduced sensitivity to anesthetic agents upon lesioning the mesopontine tegmental anesthesia area in rats depends on anesthetic type. Anesthesiology 132:535-550.
Yatziv S-l, Devor M. (2019)
Suppression of neuropathic pain by selective silencing of DRG ectopia using non-blocking concentrations of lidocaine. Pain 160:2105-2114.
Devor M. (2018)
Rethinking the causes of pain in herpes zoster and post herpetic neuralgia: the ectopic pacemaker hypothesis. Pain Reports 3:e702. p.1-9. doi:10.1097/PR9.0000000000000702
Koplovitch P, Devor M. (2018)
Dilute lidocaine suppresses ectopic neuropathic discharge in dorsal root ganglia without blocking axonal propagation: a new approach to selective pain control. Pain159:1244-1256.
Minert A, Yatziv SL, Devor M. (2017)
Location of the mesopontine neurons responsible for maintenance of anesthetic loss of consciousness. J Neurosci. 37:9320-9331.