Functional architecture of a brainstem locus for transitioning between wake and unconsciousness
August 23, 2016
The research aims at defining the functional connections between the MPTA (mesopontine tegmental anesthesia area), and its CNS projections. MPTA is a recently identified bilateral brainstem arousal nucleus, which is part of a flip-flop mechanism that switches between two stable brain states: wake and unconsciousness (reversible coma). One possible benefit that might stem from this research is a more specific, low dose pain free surgical anesthesia.